Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin

© 2020 Australian Society of Endodontology Inc This study aims to identify the optimal concentrations of triple antibiotic paste (TAP), modified triple antibiotic paste (mTAP) and double antibiotic paste (DAP) that could completely eradicate Enterococcus faecalis in dentinal tubules. One hundred and...

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Main Authors: Anat Dewi, Chawin Upara, Tadkamol Krongbaramee, Phumisak Louwakul, Tanida Srisuwan, Saengusa Khemaleelakul
Format: Journal
Published: 2020
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/70477
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-704772020-10-14T08:31:42Z Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin Anat Dewi Chawin Upara Tadkamol Krongbaramee Phumisak Louwakul Tanida Srisuwan Saengusa Khemaleelakul Dentistry © 2020 Australian Society of Endodontology Inc This study aims to identify the optimal concentrations of triple antibiotic paste (TAP), modified triple antibiotic paste (mTAP) and double antibiotic paste (DAP) that could completely eradicate Enterococcus faecalis in dentinal tubules. One hundred and ninety extracted human premolars inoculated with E. faecalis were medicated with calcium hydroxide and mixed antibiotic pastes (TAP, mTAP and DAP at 0.1, 1.25, 5, 10 and 20 mg mL−1 of each drug) for seven days before being frozen, pulverised and cultured. Specimens treated with the lowest concentration of the mixed antibiotics capable of eradicating E. faecalis were examined using scanning electron and confocal laser scanning microscopy to confirm the eradication of the microbial. TAP at 10 mg mL−1 of each drug was able to completely eliminate bacteria inside dentinal tubules, whereas mTAP and DAP required 20 mg mL−1 of each drug. Calcium hydroxide was not effective in eradicating E. faecalis inside dentinal tubules. 2020-10-14T08:31:42Z 2020-10-14T08:31:42Z 2020-01-01 Journal 17474477 13291947 2-s2.0-85090760191 10.1111/aej.12437 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85090760191&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70477
institution Chiang Mai University
building Chiang Mai University Library
continent Asia
country Thailand
Thailand
content_provider Chiang Mai University Library
collection CMU Intellectual Repository
topic Dentistry
spellingShingle Dentistry
Anat Dewi
Chawin Upara
Tadkamol Krongbaramee
Phumisak Louwakul
Tanida Srisuwan
Saengusa Khemaleelakul
Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
description © 2020 Australian Society of Endodontology Inc This study aims to identify the optimal concentrations of triple antibiotic paste (TAP), modified triple antibiotic paste (mTAP) and double antibiotic paste (DAP) that could completely eradicate Enterococcus faecalis in dentinal tubules. One hundred and ninety extracted human premolars inoculated with E. faecalis were medicated with calcium hydroxide and mixed antibiotic pastes (TAP, mTAP and DAP at 0.1, 1.25, 5, 10 and 20 mg mL−1 of each drug) for seven days before being frozen, pulverised and cultured. Specimens treated with the lowest concentration of the mixed antibiotics capable of eradicating E. faecalis were examined using scanning electron and confocal laser scanning microscopy to confirm the eradication of the microbial. TAP at 10 mg mL−1 of each drug was able to completely eliminate bacteria inside dentinal tubules, whereas mTAP and DAP required 20 mg mL−1 of each drug. Calcium hydroxide was not effective in eradicating E. faecalis inside dentinal tubules.
format Journal
author Anat Dewi
Chawin Upara
Tadkamol Krongbaramee
Phumisak Louwakul
Tanida Srisuwan
Saengusa Khemaleelakul
author_facet Anat Dewi
Chawin Upara
Tadkamol Krongbaramee
Phumisak Louwakul
Tanida Srisuwan
Saengusa Khemaleelakul
author_sort Anat Dewi
title Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
title_short Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
title_full Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
title_fullStr Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
title_full_unstemmed Optimal antimicrobial concentration of mixed antibiotic pastes in eliminating Enterococcus faecalis from root dentin
title_sort optimal antimicrobial concentration of mixed antibiotic pastes in eliminating enterococcus faecalis from root dentin
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85090760191&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70477
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