Influenza immunization does not predominantly alter levels of phenytoin, and cytochrome P-450 enzymes in epileptic patients receiving phenytoin monotherapy

• Main Authors: Atiwat Soontornpun, Natthakarn Manoyana, Nattayaporn Apaijai, Kanokwan Pinyopornpanish, Angkana Nadsasarn, Surat Tanprawate, Nipon Chattipakorn, Siriporn C. Chattipakorn
• Format: Journal
• Published: 2020
• Subjects: Medicine; Neuroscience
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85091637217&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70749
• Institution: Chiang Mai University

© 2020 Elsevier B.V. Objective: The study aims to test the effect of influenza vaccination on phenytoin, CYP2C9, and IFNγ levels in epileptic patients receiving phenytoin monotherapy Methods: Thirty-one epileptic patients receiving stable-dose phenytoin monotherapy were enrolled onto the study. Seru...