A proprotein convertase subtilisin/kexin type 9 inhibitor provides comparable efficacy with lower detriment than statins on mitochondria of oxidative muscle of obese estrogen-deprived rats

OBJECTIVES: The aim of the study was to compare the effects of atorvastatin, a proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9i), and 17β-estradiol on oxidative muscle mitochondria in a model of menopause with obesity. METHODS: Female Wistar rats consumed either a standard diet (n = 1...

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Bibliographic Details
Main Authors: Chanisa Thonusin, Patcharapong Pantiya, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Busarin Arunsak, Patchareeya Amput, Siripong Palee, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn
Format: Journal
Published: 2020
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85091807215&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70752
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Institution: Chiang Mai University
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