Perinatal Antiretroviral Intensification to Prevent Intrapartum HIV Transmission When Antenatal Antiretroviral Therapy Is Initiated Less Than 8 Weeks Before Delivery

• Main Authors: Marc Lallemant, Billy Amzal, Patumrat Sripan, Saïk Urien, Tim R. Cressey, Nicole Ngo-Giang-Huong, Virat Klinbuayaem, Boonsong Rawangban, Prapan Sabsanong, Thitiporn Siriwachirachai, Tapnarong Jarupanich, Prateep Kanjanavikai, Phaiboon Wanasiri, Suporn Koetsawang, Gonzague Jourdain, Sophie Le Coeur
• Format: Journal
• Published: 2020
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086524375&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70826
• Institution: Chiang Mai University

INTRODUCTION: Infants born to women living with HIV initiating combination antiretroviral therapy (cART) late in pregnancy are at high risk of intrapartum infection. Mother/infant perinatal antiretroviral intensification may substantially reduce this risk. METHODS: In this single-arm Bayesian trial,...