Stimulation of GLP-1 Receptor Inhibits Methylglyoxal-Induced Mitochondrial Dysfunctions in H9c2 Cardiomyoblasts: Potential Role of Epac/PI3K/Akt Pathway

• Main Authors: Narawat Nuamnaichati, Supachoke Mangmool, Nipon Chattipakorn, Warisara Parichatikanond
• Format: Journal
• Published: 2020
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086581739&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70854
• Institution: Chiang Mai University

© Copyright © 2020 Nuamnaichati, Mangmool, Chattipakorn and Parichatikanond. Accumulation of methylglyoxal (MG) contributes to oxidative stress, apoptosis, and mitochondrial dysfunction, leading to the development of type 2 diabetes and cardiovascular diseases. Inhibition of mitochondrial abnormalit...