Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients

© 2020, Japanese Society of Hematology. Pulmonary hypertension (PH) is emerging as a complication of myeloproliferative neoplasms (MPNs). This was a prospective study conducted at Chiang Mai University Hospital. The primary objective was to determine the prevalence of high echocardiographic probabil...

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Main Authors: Yanika Jindamai, Ekarat Rattarittamrong, Arintaya Phrommintikul, Lalita Yongsmith, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Adisak Tantiworawit, Lalita Norasetthada
Format: Journal
Published: 2020
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/70903
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spelling th-cmuir.6653943832-709032020-10-14T08:44:27Z Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients Yanika Jindamai Ekarat Rattarittamrong Arintaya Phrommintikul Lalita Yongsmith Pokpong Piriyakhuntorn Thanawat Rattanathammethee Sasinee Hantrakool Chatree Chai-Adisaksopha Adisak Tantiworawit Lalita Norasetthada Medicine © 2020, Japanese Society of Hematology. Pulmonary hypertension (PH) is emerging as a complication of myeloproliferative neoplasms (MPNs). This was a prospective study conducted at Chiang Mai University Hospital. The primary objective was to determine the prevalence of high echocardiographic probability of PH in MPNs patients. The secondary objectives were to determine risk factors of PH and the correlation between risk factors and peak tricuspid regurgitation velocity (TRVmax). All MPNs patients aged over 18 years, including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), were enrolled. All eligible patients underwent echocardiography for evaluation of the probability of PH in line with the 2015 European Society of Cardiology (ESC) and the European Respiratory Society (ERS) Guidelines. Sixty-six patients with a median age of 59 years were enrolled. There were 35 PV, 25 ET, and 6 PMF patients included. The prevalence of high echocardiographic probability of PH was 4.55% (2 ET and 1 PMF). Risk factors associated with high echocardiographic probability of PHT were not analyzed. There were three risk factors associated with increased TRVmax, specifically lower hemoglobin, older age, and the presence of JAK2V617F mutation. The prevalence of high echocardiographic probability of PH in MPNs patients was 4.55%. 2020-10-14T08:44:27Z 2020-10-14T08:44:27Z 2020-01-01 Journal 18653774 09255710 2-s2.0-85088363783 10.1007/s12185-020-02952-4 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088363783&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70903
institution Chiang Mai University
building Chiang Mai University Library
continent Asia
country Thailand
Thailand
content_provider Chiang Mai University Library
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Yanika Jindamai
Ekarat Rattarittamrong
Arintaya Phrommintikul
Lalita Yongsmith
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Chatree Chai-Adisaksopha
Adisak Tantiworawit
Lalita Norasetthada
Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
description © 2020, Japanese Society of Hematology. Pulmonary hypertension (PH) is emerging as a complication of myeloproliferative neoplasms (MPNs). This was a prospective study conducted at Chiang Mai University Hospital. The primary objective was to determine the prevalence of high echocardiographic probability of PH in MPNs patients. The secondary objectives were to determine risk factors of PH and the correlation between risk factors and peak tricuspid regurgitation velocity (TRVmax). All MPNs patients aged over 18 years, including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), were enrolled. All eligible patients underwent echocardiography for evaluation of the probability of PH in line with the 2015 European Society of Cardiology (ESC) and the European Respiratory Society (ERS) Guidelines. Sixty-six patients with a median age of 59 years were enrolled. There were 35 PV, 25 ET, and 6 PMF patients included. The prevalence of high echocardiographic probability of PH was 4.55% (2 ET and 1 PMF). Risk factors associated with high echocardiographic probability of PHT were not analyzed. There were three risk factors associated with increased TRVmax, specifically lower hemoglobin, older age, and the presence of JAK2V617F mutation. The prevalence of high echocardiographic probability of PH in MPNs patients was 4.55%.
format Journal
author Yanika Jindamai
Ekarat Rattarittamrong
Arintaya Phrommintikul
Lalita Yongsmith
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Chatree Chai-Adisaksopha
Adisak Tantiworawit
Lalita Norasetthada
author_facet Yanika Jindamai
Ekarat Rattarittamrong
Arintaya Phrommintikul
Lalita Yongsmith
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Chatree Chai-Adisaksopha
Adisak Tantiworawit
Lalita Norasetthada
author_sort Yanika Jindamai
title Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
title_short Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
title_full Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
title_fullStr Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
title_full_unstemmed Prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
title_sort prevalence and risk factors of high echocardiographic probability of pulmonary hypertension in myeloproliferative neoplasms patients
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088363783&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70903
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