N-acetylcysteine restored heart rate variability and prevented serious adverse events in transfusion-dependent thalassemia patients: A double-blind single center randomized controlled trial

• Main Authors: Sintip Pattanakuhar, Arintaya Phrommintikul, Adisak Tantiworawit, Somdet Srichairattanakool, Siriporn C. Chattipakorn
• Format: Journal
• Published: 2020
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086686557&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70909
• Institution: Chiang Mai University

© The author(s). Regular blood transfusions in transfusion-dependent thalassemia (TDT) patients can lead to iron overload, causing oxidative stress and sympathovagal imbalance, resulting in increased cardiac complications. We hypothesized that administrating of N-acetylcysteine (NAC) prevents seriou...