(−)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats

• Main Authors: Aman Tedasen, Sirinapa Dokduang, Yaowapa Sukpondma, Narissara Lailerd, Siribhorn Madla, Somchai Sriwiriyajan, Thidarath Rattanaburee, Varomyalin Tipmanee, Potchanapond Graidist
• Format: Journal
• Published: 2020
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088239310&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/71016
• Institution: Chiang Mai University

© 2020 Elsevier B.V. Natural and synthetic (−)-kusunokinin inhibited breast cancer, colon cancer and cholangiocarcinoma cells at the G2/M phase and induced apoptosis. However, there is no report on the action and adverse effects of (−)-kusunokinin in animal models. In this study, we investigated the...