Effects of dapagliflozin and statins attenuate renal injury and liver steatosis in high-fat/high-fructose diet-induced insulin resistant rats

• Main Authors: Laongdao Thongnak, Varanuj Chatsudthipong, Aphisek Kongkaew, Anusorn Lungkaphin
• Format: Journal
• Published: 2020
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85082725451&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/71020
• Institution: Chiang Mai University

© 2020 High-fat high-fructose diet (HFF) in obesity can induce dyslipidemia and lipid accumulation both in kidney and liver which related to insulin resistance and lipotoxicity-induced cellular damage. We investigated whether dapagliflozin with or without atorvastatin could improve lipid accumulatio...