Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator

Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. The crude n-hexane extracts Epaltes pygmaea (NH-Epx) displayed a steady larval toxicity against Culex quinquefasciatus and Aedes aegypti at the maximum dosage of 125 ppm. The level of α- and β carboxylesterase activity was d...

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Main Authors: Kesavan Amala, Raja Ganesan, Seengodan Karthi, Sengottayan Senthil-Nathan, Muthiah Chellappandian, Patcharin Krutmunag, Narayanaswamy Radhakrishnan, Faruq Mohammad, Athirstam Ponsankar, Prabhakaran Vasantha-Srinivasan
Format: Journal
Published: 2020
Subjects:
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083547135&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/71030
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-710302020-10-14T08:48:22Z Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator Kesavan Amala Raja Ganesan Seengodan Karthi Sengottayan Senthil-Nathan Muthiah Chellappandian Patcharin Krutmunag Narayanaswamy Radhakrishnan Faruq Mohammad Athirstam Ponsankar Prabhakaran Vasantha-Srinivasan Pharmacology, Toxicology and Pharmaceutics © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. The crude n-hexane extracts Epaltes pygmaea (NH-Epx) displayed a steady larval toxicity against Culex quinquefasciatus and Aedes aegypti at the maximum dosage of 125 ppm. The level of α- and β carboxylesterase activity was downregulated to the sub-lethal dosage of NH-EPx (75 ppm) in both vectors. The level of GST and CYP450 gets upregulated. The LC50 and the LC90 of NH-EPx were observed at 63 and 117 ppm and 73 and 120 ppm dosage against both the vectors, respectively. NH-EPx treatment showed morphological alterations in the gut tissues. The non-target screening recommends that NH-EPx is safe against aquatic predator. 2020-10-14T08:48:22Z 2020-10-14T08:48:22Z 2020-01-01 Journal 15569551 15569543 2-s2.0-85083547135 10.1080/15569543.2020.1748890 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083547135&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/71030
institution Chiang Mai University
building Chiang Mai University Library
continent Asia
country Thailand
Thailand
content_provider Chiang Mai University Library
collection CMU Intellectual Repository
topic Pharmacology, Toxicology and Pharmaceutics
spellingShingle Pharmacology, Toxicology and Pharmaceutics
Kesavan Amala
Raja Ganesan
Seengodan Karthi
Sengottayan Senthil-Nathan
Muthiah Chellappandian
Patcharin Krutmunag
Narayanaswamy Radhakrishnan
Faruq Mohammad
Athirstam Ponsankar
Prabhakaran Vasantha-Srinivasan
Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
description © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. The crude n-hexane extracts Epaltes pygmaea (NH-Epx) displayed a steady larval toxicity against Culex quinquefasciatus and Aedes aegypti at the maximum dosage of 125 ppm. The level of α- and β carboxylesterase activity was downregulated to the sub-lethal dosage of NH-EPx (75 ppm) in both vectors. The level of GST and CYP450 gets upregulated. The LC50 and the LC90 of NH-EPx were observed at 63 and 117 ppm and 73 and 120 ppm dosage against both the vectors, respectively. NH-EPx treatment showed morphological alterations in the gut tissues. The non-target screening recommends that NH-EPx is safe against aquatic predator.
format Journal
author Kesavan Amala
Raja Ganesan
Seengodan Karthi
Sengottayan Senthil-Nathan
Muthiah Chellappandian
Patcharin Krutmunag
Narayanaswamy Radhakrishnan
Faruq Mohammad
Athirstam Ponsankar
Prabhakaran Vasantha-Srinivasan
author_facet Kesavan Amala
Raja Ganesan
Seengodan Karthi
Sengottayan Senthil-Nathan
Muthiah Chellappandian
Patcharin Krutmunag
Narayanaswamy Radhakrishnan
Faruq Mohammad
Athirstam Ponsankar
Prabhakaran Vasantha-Srinivasan
author_sort Kesavan Amala
title Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
title_short Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
title_full Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
title_fullStr Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
title_full_unstemmed Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
title_sort larval and gut enzyme toxicity of n-hexane extract epaltes pygmaea dc. against the arthropod vectors and its non-toxicity against aquatic predator
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083547135&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/71030
_version_ 1681753010603032576

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