Phytochemical and Larvicidal Studies on Stemona curtisii: Structure of a New Pyrido[1,2-a]azepine Stemona Alkaloid

• Main Authors: Mungkornasawakul P., Pyne S.G., Jatisatienr A., Supyen D., Jatisatienr C., Lie W., Ung A.T., Skelton B.W., White A.H.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-2042428767&partnerID=40&md5=4f08db250324edbe327db28780b3b0cf; http://www.ncbi.nlm.nih.gov/pubmed/15104502; http://cmuir.cmu.ac.th/handle/6653943832/7218
• Institution: Chiang Mai University

A new pentacyclic Stemona alkaloid, stemocurtisinol (3), with a pyrido[1,2-α]azepine A,B-ring system, and the known pyrrolo[1,2-α ]azepine alkaloid oxyprotostemonine (4) have been isolated from a root extract of S. curtisii. The structure and relative stereochemistry of stemocurtisinol was determine...