Isopimarane diterpenes and flavan derivatives from the twigs of Caesalpinia furfuracea

The first phytochemical investigation of Caesalpinia furfuracea twigs led to the isolation and identification of four new compounds including two isopimarane diterpenes, caesalfurfuric acids A (1) and B (2), and two flavans, (2R)-caesalflavans A (5) and B (6), together with four known compounds, 4-e...

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Bibliographic Details
Main Authors: Siridechakorn I., Cheenpracha S., Ritthiwigrom T., Phakhodee W., Deachathai S., Machan T., Ruankeaw N., Laphookhieo S.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84891603038&partnerID=40&md5=aa5576cb6b5b8bfa63723199c5cc1b53
http://cmuir.cmu.ac.th/handle/6653943832/7269
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Institution: Chiang Mai University
Language: English
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Summary:The first phytochemical investigation of Caesalpinia furfuracea twigs led to the isolation and identification of four new compounds including two isopimarane diterpenes, caesalfurfuric acids A (1) and B (2), and two flavans, (2R)-caesalflavans A (5) and B (6), together with four known compounds, 4-epi-isopimaric acid (3), methyl (E)-3-(3,4-dihydroxyphenyl)acrylate (4), (E)-resveratrol (7) and oxyresveratrol (8). Their structures were elucidated by intensive spectroscopic analysis. Compound 1 was found to exhibit antibacterial activity against MRSA SK1 with an MIC value of 16 μg/mL. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.