Chemical stability and cytotoxicity of human insulin loaded in cationic DPPC/CTA/DDAB liposomes

• Main Authors: Manosroi A., Khositsuntiwong N., Komno C., Manosroi W., Werner R.G., Manosoi J.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.ncbi.nlm.nih.gov/pubmed/3502482; http://www.scopus.com/inward/record.url?eid=2-s2.0-79960973034&partnerID=40&md5=6b8fff7a8308b5615e03861eff340c09; http://cmuir.cmu.ac.th/handle/6653943832/7351
• Institution: Chiang Mai University

Liposomes were prepared from DPPC (dipalmitoyl phosphatidyl choline) mixed with Chol (cholesterol) and CTA [cholest-5-en-3-ol(3β)(trimethylammonio) acetate] or DDAB (dioctadecyl dimethyl ammonium bromide) at various molar ratios by chloroform film method with sonication. The most physical stable (no...