In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus

The in vitro virustatic and virucidal tests of the crude extract of Cynodon dactylon against infection with porcine reproductive and respiratory syndrome virus (PRRSV), a cause of major devastating pig disease, were described. Crude extract of C. dactylon was prepared for cytotoxicity on tissue-cult...

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Main Authors: Pringproa K., Khonghiran O., Kunanoppadol S., Potha T., Chuammitri P.
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84897558119&partnerID=40&md5=bababb33b05424d65ae7907d5a7e9040
http://cmuir.cmu.ac.th/handle/6653943832/7443
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-74432014-08-30T04:11:33Z In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus Pringproa K. Khonghiran O. Kunanoppadol S. Potha T. Chuammitri P. The in vitro virustatic and virucidal tests of the crude extract of Cynodon dactylon against infection with porcine reproductive and respiratory syndrome virus (PRRSV), a cause of major devastating pig disease, were described. Crude extract of C. dactylon was prepared for cytotoxicity on tissue-culture cells that were used to measure virustatic and virucidal activities against PRRSV. Crude extract of C. dactylon at 0.78 mg/mL showed no cytotoxicity on the cell line, and at that concentration significantly inhibited replication of PRRSV as early as 24 hours post infection (hpi). C. dactylon also inactivated PRRSV as determined by immunoperoxidase monolayer assay (IPMA) compared to the control experiments. In summary, the present study may be among the earliest studies to describe virustatic and virucidal activities of C. dactylon crude extract against PRRSV in vitro. Extracts of C. dactylon may be useful for PRRSV control and prevention on pig farms. © 2014 Kidsadagon Pringproa et al. 2014-08-30T04:11:33Z 2014-08-30T04:11:33Z 2014 Article 20420048 10.1155/2014/947589 http://www.scopus.com/inward/record.url?eid=2-s2.0-84897558119&partnerID=40&md5=bababb33b05424d65ae7907d5a7e9040 http://cmuir.cmu.ac.th/handle/6653943832/7443 English Hindawi Publishing Corporation
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The in vitro virustatic and virucidal tests of the crude extract of Cynodon dactylon against infection with porcine reproductive and respiratory syndrome virus (PRRSV), a cause of major devastating pig disease, were described. Crude extract of C. dactylon was prepared for cytotoxicity on tissue-culture cells that were used to measure virustatic and virucidal activities against PRRSV. Crude extract of C. dactylon at 0.78 mg/mL showed no cytotoxicity on the cell line, and at that concentration significantly inhibited replication of PRRSV as early as 24 hours post infection (hpi). C. dactylon also inactivated PRRSV as determined by immunoperoxidase monolayer assay (IPMA) compared to the control experiments. In summary, the present study may be among the earliest studies to describe virustatic and virucidal activities of C. dactylon crude extract against PRRSV in vitro. Extracts of C. dactylon may be useful for PRRSV control and prevention on pig farms. © 2014 Kidsadagon Pringproa et al.
format Article
author Pringproa K.
Khonghiran O.
Kunanoppadol S.
Potha T.
Chuammitri P.
spellingShingle Pringproa K.
Khonghiran O.
Kunanoppadol S.
Potha T.
Chuammitri P.
In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
author_facet Pringproa K.
Khonghiran O.
Kunanoppadol S.
Potha T.
Chuammitri P.
author_sort Pringproa K.
title In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
title_short In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
title_full In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
title_fullStr In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
title_full_unstemmed In vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
title_sort in vitro virucidal and virustatic properties of the crude extract of cynodon dactylon against porcine reproductive and respiratory syndrome virus
publisher Hindawi Publishing Corporation
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84897558119&partnerID=40&md5=bababb33b05424d65ae7907d5a7e9040
http://cmuir.cmu.ac.th/handle/6653943832/7443
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