Maternal neutralizing antibodies against a CRF01_AE primary isolate are associated with a low rate of intrapartum HIV-1 transmission

• Main Authors: Samleerat T., Thenin S., Jourdain G., Ngo-Giang-Huong N., Moreau A., Leechanachai P., Ithisuknanth J., Pagdi K., Wannarit P., Sangsawang S., Lallemant M., Barin F., Braibant M.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-64849106636&partnerID=40&md5=b5f445f76489ef40bcca11ac281460ab; http://cmuir.cmu.ac.th/handle/6653943832/777
• Institution: Chiang Mai University

Mother-to-child transmission (MTCT) of HIV-1 provides a model for studying the role of passively acquired antibodies in preventing HIV infection. We determined the titers of neutralizing antibodies (NAbs) against six primary isolates of clades B and CRF01_AE in sera from 45 transmitting and 45 nontr...