Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein

• Main Authors: Nangola S., Urvoas A., Valerio-Lepiniec M., Khamaikawin W., Sakkhachornphop S., Hong S.-S., Boulanger P., Minard P., Tayapiwatana C.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.ncbi.nlm.nih.gov/pubmed/3502482; http://www.scopus.com/inward/record.url?eid=2-s2.0-84857126902&partnerID=40&md5=d4d05bc08c0bdfc0cd19157528a7d49f; http://cmuir.cmu.ac.th/handle/6653943832/802
• Institution: Chiang Mai University

Background: Ankyrins are cellular mediators of a number of essential protein-protein interactions. Unlike intrabodies, ankyrins are composed of highly structured repeat modules characterized by disulfide bridge-independent folding. Artificial ankyrin molecules, designed to target viral components, m...