Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract

The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavo...

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Main Authors: Singhatong S., Leelarungrayub D., Chaiyasut C.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e
http://cmuir.cmu.ac.th/handle/6653943832/862
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-8622014-08-29T09:02:15Z Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract Singhatong S. Leelarungrayub D. Chaiyasut C. The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H2O2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect. 2014-08-29T09:02:15Z 2014-08-29T09:02:15Z 2010 Article 19960875 http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e http://cmuir.cmu.ac.th/handle/6653943832/862 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H2O2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect.
format Article
author Singhatong S.
Leelarungrayub D.
Chaiyasut C.
spellingShingle Singhatong S.
Leelarungrayub D.
Chaiyasut C.
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
author_facet Singhatong S.
Leelarungrayub D.
Chaiyasut C.
author_sort Singhatong S.
title Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
title_short Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
title_full Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
title_fullStr Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
title_full_unstemmed Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
title_sort antioxidant and toxicity activities of artocarpus lakoocha roxb. heartwood extract
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e
http://cmuir.cmu.ac.th/handle/6653943832/862
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