Association between detection of HIV-1 DNA resistance mutations by a sensitive assay at initiation of antiretroviral therapy and virologic failure

• Main Authors: Jourdain G., Wagner T.A., Ngo-Giang-Huong N., Sirirungsi W., Klinbuayaem V., Fregonese F., Nantasen I., Techapornroong M., Halue G., Nilmanat A., Wittayapraparat P., Chalermpolprapa V., Pathipvanich P., Yuthavisuthi P., Frenkel L.M., Lallemant M.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951790626&partnerID=40&md5=c35a39cae10a88460aaf88f658419c29; http://cmuir.cmu.ac.th/handle/6653943832/863
• Institution: Chiang Mai University

Background. Antiretroviral therapy (ART) has become more available throughout the developing world during the past 5 years. The World Health Organization recommends nonnucleoside reverse-transcriptase inhibitor-based regimens as initial ART. However, their efficacy may be compromised by resistance m...