Role of CD137 signaling in dengue virus-mediated apoptosis

• Main Authors: Nagila A., Netsawang J., Srisawat C., Noisakran S., Morchang A., Yasamut U., Puttikhunt C., Kasinrerk W., Malasit P., Yenchitsomanus P.-T., Limjindaporn T.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-79960050971&partnerID=40&md5=b02041c142509105e692420858934fb5; http://cmuir.cmu.ac.th/handle/6653943832/876
• Institution: Chiang Mai University

Hepatic dysfunction is a well recognized feature of dengue virus (DENV) infection. However, molecular mechanisms of hepatic injury are still poorly understood. A complex interaction between DENV and the host immune response contributes to DENV-mediated tissue injury. DENV capsid protein (DENV C) phy...