Once- versus twice-daily lopinavir/ritonavir tablets in virologically suppressed, HIV-infected, treatment-experienced children: Comparative pharmacokinetics and virological outcome after switching to once-daily lopinavir/ritonavir

• Main Authors: Chokephaibulkit K., Nuntarukchaikul M., Phongsamart W., Wittawatmongkol O., Lapphra K., Vanprapar N., Cressey T.R.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84869462249&partnerID=40&md5=afdc589e473e64d7a54b76da5bcdce53; http://cmuir.cmu.ac.th/handle/6653943832/903
• Institution: Chiang Mai University

Objectives: Data on lopinavir/ritonavir tablets administered once daily in children are limited. We compared the pharmacokinetics (PK) of lopinavir/ritonavir twice daily versus once daily in virologically suppressed, HIV-infected children, and assessed the virological outcome, at 48 weeks, in childr...