Increased Risk of Q151M and K65R Mutations in Patients Failing Stavudine-Containing First-Line Antiretroviral Therapy in Cambodia

• Main Authors: Nouhin J., Madec Y., Ngo-Giang-Huong N., Ferradini L., Nerrienet E.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-84883376450&partnerID=40&md5=788369348d0a640fbbd652da17568c9b; http://cmuir.cmu.ac.th/handle/6653943832/921
• 機構: Chiang Mai University

Background:Multi-nucleos(t)ide resistance (MNR) mutations including Q151M, K65R mutations, and insertion at codon 69 of HIV-1 reverse transcriptase coding region may confer resistance to all molecules of nucleos(t)ide reverse transcriptase inhibitors (NRTI). The presence of these mutations is an eme...