Chemical constituents from a Thai tunicate, Didemnum sp.
Thesis (M.Sc. in Pharm.)--Chulalongkorn University, 1997
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2010
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th-cuir.126422010-05-10T10:31:47Z Chemical constituents from a Thai tunicate, Didemnum sp. สารเคมีจากทูนิเคต, Didemnum sp. ของไทย Pongsatorn Limsiriwong Khanit Suwanborirux Surattana Amnuoypol Chulalongkorn University. Graduate School Chemistry, Analytic Tunicata -- Thailand Didemnidae Thesis (M.Sc. in Pharm.)--Chulalongkorn University, 1997 Four halogenated pyrrolo[2,3-d]pyrimidine nucleosides were isolated from a Thai tunicate, Didemnum sp.: including three known compounds, 4-amino-7-(5'-deoxyribos-1'beta-yl)-5-iodopyrrolo[2,3-d]pyrimidine, 4-amino-7-(5'-deoxyribos-1'beta-yl)-5-bromopyrrolo[2,3-d]pyrimidine, and 4-amino-7-(5'-deoxyxylos-1'beta-yl)-5-iodo-pyrrolo[2,3-d]pyrimidine and a new derivative, 4-amino-7-(5'-deoxyxylos-1'beta-yl)-5-bromopyrrolo[2,3-d]pyrimidine. The structures and relative stereochemistry of the compounds were elucidated through extensive analyses of their uv, ir, ms, 1H and 13C nmr spectral data, especially NOE and LCMS techniques, as well as comparison with the data of related compounds. จากการแยกสกัดสารจากทูนิเคตไทย, Didemnum sp. สามารถแยกสารในกลุ่มนิวคลีโอไซด์ได้ 4 ชนิด ได้แก่ 4-amino-7-(5'-deoxyribos-1'beta-yl)-5-iodopyrrolo[2,3-d]pyrimidine, 4-amino-7-(5'-deoxyribos-1'beta-yl)-5-bromopyrrolo[2,3-d]pyrimidine, 4-amino-7-(5'-deoxyxylos-1'beta-yl)-5-iodopyrrolo[2,3-d]pyrimidine และ 4-amino-7-(5'-deoxyxylos-1'beta-yl)-5-bromopyrrolo[2,3-d]pyrimidine ซึ่งสารตัวสุดท้ายยังไม่เคยมีรายงานมาก่อน การพิสูจน์สูตรโครงสร้างของสารทั้ง 4 ชนิดนี้ทำโดยการวิเคราะห์ข้อมูลจากสเปคตรัมของ uv, ir, ms, 1H และ 13C nmr โดยเฉพาะอย่างยิ่งจากข้อมูลที่ได้จากเทคนิค NOE และ LCMS ร่วมกับการเปรียบเทียบข้อมูลกับสารชนิดอื่น ที่มีโครงสร้างทางเคมีที่สัมพันธ์กัน 2010-05-10T10:31:46Z 2010-05-10T10:31:46Z 1997 Thesis 9746371282 http://cuir.car.chula.ac.th/handle/123456789/12642 en Chulalongkorn University 422852 bytes 262857 bytes 786791 bytes 430886 bytes 503125 bytes 167239 bytes 760412 bytes application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf Thailand Chulalongkorn University |
| institution |
Chulalongkorn University |
| building |
Chulalongkorn University Library |
| country |
Thailand |
| collection |
Chulalongkorn University Intellectual Repository |
| language |
English |
| topic |
Chemistry, Analytic Tunicata -- Thailand Didemnidae |
| spellingShingle |
Chemistry, Analytic Tunicata -- Thailand Didemnidae Pongsatorn Limsiriwong Chemical constituents from a Thai tunicate, Didemnum sp. |
| description |
Thesis (M.Sc. in Pharm.)--Chulalongkorn University, 1997 |
| author2 |
Khanit Suwanborirux |
| author_facet |
Khanit Suwanborirux Pongsatorn Limsiriwong |
| format |
Theses and Dissertations |
| author |
Pongsatorn Limsiriwong |
| author_sort |
Pongsatorn Limsiriwong |
| title |
Chemical constituents from a Thai tunicate, Didemnum sp. |
| title_short |
Chemical constituents from a Thai tunicate, Didemnum sp. |
| title_full |
Chemical constituents from a Thai tunicate, Didemnum sp. |
| title_fullStr |
Chemical constituents from a Thai tunicate, Didemnum sp. |
| title_full_unstemmed |
Chemical constituents from a Thai tunicate, Didemnum sp. |
| title_sort |
chemical constituents from a thai tunicate, didemnum sp. |
| publisher |
Chulalongkorn University |
| publishDate |
2010 |
| url |
http://cuir.car.chula.ac.th/handle/123456789/12642 |
| _version_ |
1681413194882482176 |