Leukocyte-endothelial cell interaction is attenuated by low-intensity exercise training and vitamin C supplementation in diabetic rats

The increased leukocyte-EC adherence in diabetic rats is significantly related to increased ROS, based on lower MDA levels. Vitamin C supplementation and regular low-intensity exercise training can prevent these deleterious effects, including hypertension, cardiac hypertrophy, hypertriglyceridemia...

Full description

Saved in:
Bibliographic Details
Main Authors: Daroonwan Chakraphan, Patarin Sridulyakul, Bundit Thipakorn, Srichitra Bunnag, Huxley, Virginia H., Suthiluk Patumraj
Other Authors: Chulalongkorn University. School of Sports Science
Format: Article
Language:English
Published: Chulalongkorn University 2010
Subjects:
Online Access:http://cuir.car.chula.ac.th/handle/123456789/13619
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chulalongkorn University
Language: English
Description
Summary:The increased leukocyte-EC adherence in diabetic rats is significantly related to increased ROS, based on lower MDA levels. Vitamin C supplementation and regular low-intensity exercise training can prevent these deleterious effects, including hypertension, cardiac hypertrophy, hypertriglyceridemia, and leukocyte-EC adherence. Vitamin C supplementation combined with low-intensity exercise training is highly effective in preventing diabetic cardiovascular complications.