Leukocyte-endothelial cell interaction is attenuated by low-intensity exercise training and vitamin C supplementation in diabetic rats

Leukocyte-endothelial cell interaction is attenuated by low-intensity exercise training and vitamin C supplementation in diabetic rats

The increased leukocyte-EC adherence in diabetic rats is significantly related to increased ROS, based on lower MDA levels. Vitamin C supplementation and regular low-intensity exercise training can prevent these deleterious effects, including hypertension, cardiac hypertrophy, hypertriglyceridemia...

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Bibliographic Details
Main Authors: Daroonwan Chakraphan, Patarin Sridulyakul, Bundit Thipakorn, Srichitra Bunnag, Huxley, Virginia H., Suthiluk Patumraj
Other Authors: Chulalongkorn University. School of Sports Science
Format: Article
Language:English
Published: Chulalongkorn University 2010
Subjects:
Leucocytes
Exercise
Vitamin C
Diabetics
Diabetic rat
Endothelial dysfunction
Exercise training
Leukocyte
Online Access:http://cuir.car.chula.ac.th/handle/123456789/13619
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Institution: Chulalongkorn University
Language: English
Description
Summary:The increased leukocyte-EC adherence in diabetic rats is significantly related to increased ROS, based on lower MDA levels. Vitamin C supplementation and regular low-intensity exercise training can prevent these deleterious effects, including hypertension, cardiac hypertrophy, hypertriglyceridemia, and leukocyte-EC adherence. Vitamin C supplementation combined with low-intensity exercise training is highly effective in preventing diabetic cardiovascular complications.

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