Immobilization of RGD Peptides on surface of Tyrosine-Derived Polycarbonate to enhance cell adhesion and proliferation

• Main Authors: Voravee P. Hoven, Kohn, Joachim, Adisorn Poopattanapong
• Other Authors: Chulalongkorn University. Faculty of Science
• Format: Technical Report
• Language: English
• Published: Chulalongkorn University 2008
• Subjects: Tyrosine; Polycarbonates; Immobilized cells; Peptides; Amino acids
• Online Access: http://cuir.car.chula.ac.th/handle/123456789/8297
• Institution: Chulalongkorn University

This research has focused on chemical immobilization of RGD-containing peptides (RGD, RGDS, GRGDS) on the surface of tyrosine-derived polycarbonates having carboxyl pendant groups, poly(DTE-co-20%DT carbonate) through a two-step reaction. The first step involved an activation of carboxyl groups by N...