Filamentous structures in dengue type 3 virus infected mouse neurones
Dengue type 3 (H 87) virus was inoculated into suckling mouse brain and the animals were sacrified at 24 hr intervals. Parallel filamentous structures were found in infected neurones in close association with virus particles in the distended endoplasmic cisternae. They were usually arranged in a cry...
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Main Authors: | , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/10624 |
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Institution: | Mahidol University |
Summary: | Dengue type 3 (H 87) virus was inoculated into suckling mouse brain and the animals were sacrified at 24 hr intervals. Parallel filamentous structures were found in infected neurones in close association with virus particles in the distended endoplasmic cisternae. They were usually arranged in a crystalloid pattern, oriented in different directions within the cisternae. Faint helical features were sometimes observed. The filamentous structures measured 15-25 nm in width and varied in length. Their possible involvement with viral material or a viral core is postulated. |
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