Filamentous structures in dengue type 3 virus infected mouse neurones

Dengue type 3 (H 87) virus was inoculated into suckling mouse brain and the animals were sacrified at 24 hr intervals. Parallel filamentous structures were found in infected neurones in close association with virus particles in the distended endoplasmic cisternae. They were usually arranged in a cry...

Full description

Saved in:
Bibliographic Details
Main Authors: S. Sriurairatna, N. Bhamarapravati, S. Onishi
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/10624
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University
Description
Summary:Dengue type 3 (H 87) virus was inoculated into suckling mouse brain and the animals were sacrified at 24 hr intervals. Parallel filamentous structures were found in infected neurones in close association with virus particles in the distended endoplasmic cisternae. They were usually arranged in a crystalloid pattern, oriented in different directions within the cisternae. Faint helical features were sometimes observed. The filamentous structures measured 15-25 nm in width and varied in length. Their possible involvement with viral material or a viral core is postulated.