Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy

The macrophage migration inhibition technique was employed to study the development of human maternal cell mediated immune reactions to placental antigens during the first pregnancy. Cell mediated immune reaction to pooled antigens from five placentas could not be demonstrated during the first trime...

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Main Authors: V. Youtananukorn, P. Matangkasombut, V. Osathanondh
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/10627
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Institution: Mahidol University
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spelling th-mahidol.106272018-04-19T20:59:06Z Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy V. Youtananukorn P. Matangkasombut V. Osathanondh Mahidol University Immunology and Microbiology Medicine The macrophage migration inhibition technique was employed to study the development of human maternal cell mediated immune reactions to placental antigens during the first pregnancy. Cell mediated immune reaction to pooled antigens from five placentas could not be demonstrated during the first trimester. In the 4th month, peripheral blood leucocytes from seven out of eight primigravidous women tested were reactive to placental antigens. The one nonreactor became reactive by the 5th month. All of the primigravidous women tested during subsequent months were reactive. Serial studies suggested a gradual increase in the degree of cell mediated immune reactivity in the course of the first pregnancy. 2018-04-19T13:57:09Z 2018-04-19T13:57:09Z 1974-01-01 Article Clinical and Experimental Immunology. Vol.16, No.4 (1974), 593-598 00099104 2-s2.0-0016375069 https://repository.li.mahidol.ac.th/handle/123456789/10627 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0016375069&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Immunology and Microbiology
Medicine
spellingShingle Immunology and Microbiology
Medicine
V. Youtananukorn
P. Matangkasombut
V. Osathanondh
Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
description The macrophage migration inhibition technique was employed to study the development of human maternal cell mediated immune reactions to placental antigens during the first pregnancy. Cell mediated immune reaction to pooled antigens from five placentas could not be demonstrated during the first trimester. In the 4th month, peripheral blood leucocytes from seven out of eight primigravidous women tested were reactive to placental antigens. The one nonreactor became reactive by the 5th month. All of the primigravidous women tested during subsequent months were reactive. Serial studies suggested a gradual increase in the degree of cell mediated immune reactivity in the course of the first pregnancy.
author2 Mahidol University
author_facet Mahidol University
V. Youtananukorn
P. Matangkasombut
V. Osathanondh
format Article
author V. Youtananukorn
P. Matangkasombut
V. Osathanondh
author_sort V. Youtananukorn
title Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
title_short Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
title_full Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
title_fullStr Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
title_full_unstemmed Onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
title_sort onset of human maternal cell mediated immune reaction to placental antigens during the first pregnancy
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/10627
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