Autoradiographic study of DNA synthesis of pancreatic cells of alloxan diabetic rats

Sexually immature rats, 20 to 28 days of age, were induced diabetics by a single diabetogenic dose of alloxan. Autoradiography using 3 H thymidine revealed statistically significant increases in the nuclear labeling of the acinar cell, ductular epithelial cell and islet cell of the alloxan diabetic...

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Bibliographic Details
Main Author: W. I. Na Ayuthya
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/10657
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Institution: Mahidol University
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Summary:Sexually immature rats, 20 to 28 days of age, were induced diabetics by a single diabetogenic dose of alloxan. Autoradiography using 3 H thymidine revealed statistically significant increases in the nuclear labeling of the acinar cell, ductular epithelial cell and islet cell of the alloxan diabetic rats. The possible roles of these cells in the regeneration of the islet β cell after alloxan diabetes are considered.