Acetaminophen psi parameter: a useful tool to quantify hepatotoxicity risk in acute acetaminophen overdose

• Main Authors: Summon Chomchai, สัมมน โฉมฉาย, Chulathida Chomchai, จุฬธิดา โฉมฉาย, Anusornsuwan, T.
• Other Authors: Mahidol University. Mahidol University International College. Science Division.
• Format: Article
• Language: English
• Published: 2015
• Subjects: Analgesics; Gut and hepatotoxicity; Paracetamol
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/10957
• Institution: Mahidol University

Context.The risk of hepatotoxicity secondary to acute acetaminophen overdose is related to serum acetaminophen concentration and lag time from ingestion to N-acetylcysteine (NAC) therapy. Psi (Greek letter ψ) is a toxicokinetic parameter that takes the acetaminophen level at 4 h post-ingestion ([APA...