Changes in spinal inhibitory networks induced by furosemide in humans

• Main Authors: Wanalee Klomjai, Lackmy-Vall´ee, Alexandra, Katz, Rose, Bussel, Bernard, Bensmail, Djamel, Lamy, Jean-Charles, Roche, Nicolas
• Other Authors: Mahidol University. Faculty of Physical Therapy
• Format: Article
• Language: English
• Published: 2018
• Subjects: spinal; human
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/10989
• Institution: Mahidol University

Abstract During neural development in animals, GABAergic and glycinergic neurons are first excitatory, and then become inhibitory in the mature state. This developmental shift is due mainly to strong expression of the cation-chloride K–Cl cotransporter 2 (KCC2) and down-regulation of Na–K–Cl cotr...