Characteristics of drugs that penetrate the preimplantation blastocyst

• المؤلف الرئيسي: Amnuay Thithapandha
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/11070

Experiments were performed to evaluate the role of physicochemical properties of drugs and chemicals in determining their passage into the preimplantation blastocysts of 6-day pregnant rabbits. It was found that compounds with molecular weight less than ouabain (mol. wt 585) readily traversed the bl...