Functional genomics unique to week 20 post wounding in the deep cone/fat dome of the duroc/yorkshire porcine model of fibroproliferative scarring

• Main Authors: Loren H. Engrav, Christopher K. Tuggle, Kathleen F. Kerr, Kathy Q. Zhu, Surawej Numhom, Oliver P. Couture, Richard P. Beyer, Anne M. Hocking, Gretchen J. Carrougher, Maria Luiza C. Ramos, Matthew B. Klein, Nicole S. Gibran
• Other Authors: University of Washington, Seattle
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11320
• Institution: Mahidol University

Background: Hypertrophic scar was first described over 100 years ago; PubMed has more than 1,000 references on the topic. Nevertheless prevention and treatment remains poor, because 1) there has been no validated animal model; 2) human scar tissue, which is impossible to obtain in a controlled manne...