High prevalence of an anti-hypertriglyceridemic variant of the MLXIPL gene in Central Asia

• Main Authors: Kazuhiro Nakayama, Yoshiko Yanagisawa, Ayumi Ogawa, Yuumi Ishizuka, Lkhagvasuren Munkhtulga, Phitaya Charupoonphol, Somjit Supannnatas, Stevenson Kuartei, Ulziiburen Chimedregzen, Yoshiro Koda, Takafumi Ishida, Yasuo Kagawa, Sadahiko Iwamoto
• Other Authors: Jichi Medical University
• Format: Review
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11403
• Institution: Mahidol University

MLXIPL is a transcription factor integral to the regulation of glycolysis and lipogenesis in the liver. Common variants of the MLXIPL gene (MLXIPL) are known to influence plasma triglyceride levels in people of European descent. As MLXIPL has a key role in energy storage, genetic variations of the M...