Evaluation of six commercial point-of-care tests for diagnosis of acute dengue infections: The need for combining NS1 antigen and IgM/IgG antibody detection to achieve acceptable levels of accuracy

• Main Authors: Stuart D. Blacksell, Richard G. Jarman, Mark S. Bailey, Ampai Tanganuchitcharnchai, Kemajittra Jenjaroen, Robert V. Gibbons, Daniel H. Paris, Ranjan Premaratna, H. Janaka De Silva, David G. Lalloo, Nicholas P J Day
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11424

Six assays were evaluated in this study to determine their suitability for the diagnosis of acute dengue infection using samples from 259 Sri Lankan patients with acute fevers (99 confirmed dengue cases and 160 patients with other confirmed acute febrile illnesses): (i) the Merlin dengue fever IgG...