Identification of motifs of Burkholderia pseudomallei BimA required for intracellular motility, actin binding, and actin polymerization

• Main Authors: Chayada Sitthidet, Sunee Korbsrisate, Abigail N. Layton, Terence R. Field, Mark P. Stevens, Joanne M. Stevens
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11573

Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires BimA (Burkholderia intracellular motility A). The mechanism by which BimA mediates actin assembly at the bacterial pole is ill-defined. Toward an understanding of the regions of B. pseudomallei BimA required for intr...