Promoter methylation and genetic polymorphism of glutathione S-transferase P1 gene (GSTP1) in Thai breast-cancer patients

The GSTP1 gene encodes for a detoxification enzyme involved in protecting cells from carcinogens. In breast cancer, GSTP1 polymorphisms may produce lower effective enzyme detoxification properties and GSTP1 promoter hypermethylation may result in inactivation of GSTP1 expression. We therefore hypoth...

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Bibliographic Details
Main Authors: Tanett Pongtheerat, Supparit Pakdeethai, Wichai Purisa, Sunanta Chariyalertsak, Songsak Petmitr
Other Authors: Rangsit University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/11633
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Institution: Mahidol University