Induced autophagy reduces virus output in dengue infected monocytic cells

• Main Authors: Mingkwan Panyasrivanit, Michael P. Greenwood, David Murphy, Ciro Isidoro, Prasert Auewarakul, Duncan R. Smith
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11995

While several studies have shown a role for autophagy in the replication of dengue virus (DENV), these studies have been performed in directly infected cells. However, in severe cases of DENV infection the critical cell in the disease is believed to be monocytes which are poorly infected directly, b...