Superoxide dismutase C is required for intracellular survival and virulence of burkholderia pseudomallei

• Main Authors: Muthita Vanaporn, Matthew Wand, Stephen L. Michell, Mitali Sarkar-Tyson, Philip Ireland, Stan Goldman, Chidchamai Kewcharoenwong, Darawan Rinchai, Ganjana Lertmemongkolchai, Richard W. Titball
• Other Authors: University of Exeter
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/12013
• Institution: Mahidol University

Burkholderia pseudomallei is an intracellular pathogen and the causative agent of melioidosis, a life-threatening disease of humans. Within host cells, superoxide is an important mediator of pathogen killing. In this study, we have identified the B. pseudomallei K96243 sodC gene, shown that it has s...