Correlation of susceptibility of Cryptococcus neoformans to amphotericin B with clinical outcome

• Main Authors: R. A. Larsen, M. Bauer, P. Pitisuttithum, A. Sanchez, S. Tansuphaswadikul, V. Wuthiekanun, S. J. Peacock, A. J.H. Simpson, A. W. Fothergill, M. G. Rinaldi, B. Bustamante, A. M. Thomas, R. Altomstone, N. P.J. Day, N. J. White
• Other Authors: University of Southern California
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/12215
• Institution: Mahidol University

Testing of Cryptococcus neoformans for susceptibility to antifungal drugs by standard microtiter methods has not been shown to correlate with clinical outcomes. This report describes a modified quantitative broth macrodilution susceptibility method showing a correlation with both the patient's...