Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute scrub typhus infection

• Main Authors: Daniel H. Paris, Stuart D. Blacksell, Pruksa Nawtaisong, Kemajittra Jenjaroen, Achara Teeraratkul, Wirongrong Chierakul, Vanaporn Wuthiekanun, Pacharee Kantipong, Nicholas P J Day
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/12360

Background: There is an urgent need to develop rapid and accurate point-of-care (POC) technologies for acute scrub typhus diagnosis in low-resource, primary health care settings to guide clinical therapy. Methodology/Principal Findings: In this study we present the clinical evaluation of loop-mediat...