Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash

• Main Authors: Soranun Chantarangsu, Taisei Mushiroda, Surakameth Mahasirimongkol, Sasisopin Kiertiburanakul, Somnuek Sungkanuparph, Weerawat Manosuthi, Woraphot Tantisiriwat, Angkana Charoenyingwattana, Thanyachai Sura, Atsushi Takahashi, Michiaki Kubo, Naoyuki Kamatani, Wasun Chantratita, Yusuke Nakamura
• Other Authors: Chulalongkorn University
• Format: Review
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/12379
• Institution: Mahidol University

Background. We aimed to identify disease-predisposing variations with nevirapine-induced rash using genome-wide single-nucleotide polymorphisms (SNPs) as genetic markers. Methods. A genome-wide association study (GWAS) was performed using-550000 markers in 72 human immunodeficiency virus (HIV)-infec...