Risk factors for developing delirium in older patients admitted to general medical wards.

Delirium in older patients is common and leads to poor clinical outcomes. It is, however, preventable if its risk factors are identified and modified accordingly. To determine risk factors associated with delirium in hospitalized older patients admitted to general medical wards at Siriraj Hospital....

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Main Authors: Varalak Srinonprasert, Sorapop Pakdeewongse, Jintana Assanasen, Waricha Eiamjinnasuwat, Achara Sirisuwat, Duangsawang Limmathuroskul, Rungnirand Praditsuwan
Other Authors: Mahidol University
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Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/12652
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spelling th-mahidol.126522018-05-03T15:36:06Z Risk factors for developing delirium in older patients admitted to general medical wards. Varalak Srinonprasert Sorapop Pakdeewongse Jintana Assanasen Waricha Eiamjinnasuwat Achara Sirisuwat Duangsawang Limmathuroskul Rungnirand Praditsuwan Mahidol University Medicine Delirium in older patients is common and leads to poor clinical outcomes. It is, however, preventable if its risk factors are identified and modified accordingly. To determine risk factors associated with delirium in hospitalized older patients admitted to general medical wards at Siriraj Hospital. A prospective observational study was conducted at general medical wards, Siriraj Hospital. All consecutive patients aged 70 years or older admitted during study period were assessed and followed until discharge. A diagnosis of delirium was made if patients developed symptoms which fulfilled DSM IV criteria. Information regarding demographic data, co-morbid illnesses, preexisting cognitive status and functional status was collected at admission. Factorf associated with delirium were analyzed using logistic regression models. Risk factors associated with developing delirium identified from univariate analysis were female gender, age more than 80 years-old, having 4 or more co-morbidities, azothemia, hyponatremia, presence of infection, severe illness, preexisting dementia, depression, and impaired basic activities of daily living. After adjusted in multivariate analysis; factors those remained statistically significant were preexisting dementia (OR = 5.52, 95% CI = 2.51-12.14), severe illness (OR = 5.18, 95% CI = 2.10-12.76) presence of infection (OR = 2.54, 95% CI = 1.15-5.61) and azothemia (OR = 2.55, 95% CI = 1.205.40). Pre-existing dementia and illness severity were strongly associated with developing delirium in older patients in the present study, which is concordant with previous studies. Other factors such as presence of infection and azothemia are modifiable factors that could potentially be important targets, along with other factors identified in the present study, for implementing intervention in order to prevent delirium in this population. 2018-05-03T08:36:06Z 2018-05-03T08:36:06Z 2011-02-01 Article Journal of the Medical Association of Thailand = Chotmaihet thangphaet. Vol.94 Suppl 1, (2011) 01252208 2-s2.0-80054830994 https://repository.li.mahidol.ac.th/handle/123456789/12652 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80054830994&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Varalak Srinonprasert
Sorapop Pakdeewongse
Jintana Assanasen
Waricha Eiamjinnasuwat
Achara Sirisuwat
Duangsawang Limmathuroskul
Rungnirand Praditsuwan
Risk factors for developing delirium in older patients admitted to general medical wards.
description Delirium in older patients is common and leads to poor clinical outcomes. It is, however, preventable if its risk factors are identified and modified accordingly. To determine risk factors associated with delirium in hospitalized older patients admitted to general medical wards at Siriraj Hospital. A prospective observational study was conducted at general medical wards, Siriraj Hospital. All consecutive patients aged 70 years or older admitted during study period were assessed and followed until discharge. A diagnosis of delirium was made if patients developed symptoms which fulfilled DSM IV criteria. Information regarding demographic data, co-morbid illnesses, preexisting cognitive status and functional status was collected at admission. Factorf associated with delirium were analyzed using logistic regression models. Risk factors associated with developing delirium identified from univariate analysis were female gender, age more than 80 years-old, having 4 or more co-morbidities, azothemia, hyponatremia, presence of infection, severe illness, preexisting dementia, depression, and impaired basic activities of daily living. After adjusted in multivariate analysis; factors those remained statistically significant were preexisting dementia (OR = 5.52, 95% CI = 2.51-12.14), severe illness (OR = 5.18, 95% CI = 2.10-12.76) presence of infection (OR = 2.54, 95% CI = 1.15-5.61) and azothemia (OR = 2.55, 95% CI = 1.205.40). Pre-existing dementia and illness severity were strongly associated with developing delirium in older patients in the present study, which is concordant with previous studies. Other factors such as presence of infection and azothemia are modifiable factors that could potentially be important targets, along with other factors identified in the present study, for implementing intervention in order to prevent delirium in this population.
author2 Mahidol University
author_facet Mahidol University
Varalak Srinonprasert
Sorapop Pakdeewongse
Jintana Assanasen
Waricha Eiamjinnasuwat
Achara Sirisuwat
Duangsawang Limmathuroskul
Rungnirand Praditsuwan
format Article
author Varalak Srinonprasert
Sorapop Pakdeewongse
Jintana Assanasen
Waricha Eiamjinnasuwat
Achara Sirisuwat
Duangsawang Limmathuroskul
Rungnirand Praditsuwan
author_sort Varalak Srinonprasert
title Risk factors for developing delirium in older patients admitted to general medical wards.
title_short Risk factors for developing delirium in older patients admitted to general medical wards.
title_full Risk factors for developing delirium in older patients admitted to general medical wards.
title_fullStr Risk factors for developing delirium in older patients admitted to general medical wards.
title_full_unstemmed Risk factors for developing delirium in older patients admitted to general medical wards.
title_sort risk factors for developing delirium in older patients admitted to general medical wards.
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/12652
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