An Examination of Complement Proteins on Membranes of Paroxysmal Nocturnal Haemoglobinuria (PNH) and PNH‐like Red Cells
Summary. Proteins obtained from membranes of PNH erythrocytes and of red cells treated with 2‐aminoethylisothiouronium bromide (AET) following lysis in acidified serum (Ham's test) were compared by sodium dodecylsulphate‐polyacrylamide gel electrophoresis. The peptide patterns were identical,...
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| Main Authors: | , , |
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| Format: | Article |
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2018
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/13256 |
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| Institution: | Mahidol University |
| Summary: | Summary. Proteins obtained from membranes of PNH erythrocytes and of red cells treated with 2‐aminoethylisothiouronium bromide (AET) following lysis in acidified serum (Ham's test) were compared by sodium dodecylsulphate‐polyacrylamide gel electrophoresis. The peptide patterns were identical, providing support that AET‐treated red cells afford a suitable experimental substitute for PNH red cells in studies involving complement fixation. Copyright © 1979, Wiley Blackwell. All rights reserved |
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