Preliminary report: Homology modeling of Human Ryanodine Receptor-1

• Main Authors: Waraphan Toniti, Pranom Puchadapirom, Aekkapot Chamkasem
• Other Authors: Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
• Format: Article
• Language: English
• Published: 2018
• Subjects: Human RyR1; Calcium channel; Skeletal muscle; Homology modeling; in silico; Journal of Applied Animal Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13324
• Institution: Mahidol University

Excitation-contraction (E-C) coupling is the series of events in which an electrical stimulus is converted into a mechanical contraction. Ryanodine receptors (RyRs), the Ca2+ release channels, located at the sarcoplasmic reticulum membrane and played role in E-C coupling. In this study, human RyR1...