QSAR study of anti-prion activity of 2-aminothiazoles

• Main Authors: Prasit Mandi, Chanin Nantasenamat, Kakanand Srungboonmee, Chartchalerm Isarankura-Na-Ayudhya, Virapong Prachayasittikul
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13383

2-aminothiazoles is a class of compounds capable of treating life-threatening prion diseases. QSAR studies on a set of forty-seven 2-aminothiazole derivatives possessing anti-prion activity were performed using multivariate analysis, which comprised of multiple linear regression (MLR), artificial ne...