Deficient signaling via Alk2 (Acvr1) leads to Bicuspid aortic valve development
Bicuspid aortic valve (BAV) is the most common congenital cardiac anomaly in humans. Despite recent advances, the molecular basis of BAV development is poorly understood. Previously it has been shown that mutations in the Notch1 gene lead to BAV and valve calcification both in human and mice, and mi...
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Main Authors: | Penny S. Thomas, Somyoth Sridurongrit, Pilar Ruiz-Lozano, Vesa Kaartinen |
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Other Authors: | University of Michigan, Ann Arbor |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/13463 |
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Institution: | Mahidol University |
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