Apical acidity decreases inhibitory effect of omeprazole on Mg<sup>2+</sup>absorption and claudin-7 and -12 expression in Caco-2 monolayers

Clinical studies reported hypomagnesaemia in long-term omeprazole usage that was probably due to intestinal Mg 2+ wasting. Our previous report demonstrated the inhibitory effect of omeprazole on passive Mg 2+ transport across Caco-2 monolayers. The present study aimed to identify the underlying mech...

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Bibliographic Details
Main Authors: Narongrit Thongon, Nateetip Krishnamra
Other Authors: Burapha University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13570
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Institution: Mahidol University