Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

The transcription factor nuclear factor-E2-related factor 2 (Nrf2) is a key regulator for induction of hepatic detoxification and antioxidant mechanisms, as well as for certain hepatobiliary transporters. To examine the role of Nrf2 in bile acid homeostasis and cholestasis, we assessed the determina...

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Bibliographic Details
Main Authors: Jittima Weerachayaphorn, Albert Mennone, Carol J. Soroka, Kathy Harry, Lee R. Hagey, Thomas W. Kensler, James L. Boyer
Other Authors: Yale University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13747
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Institution: Mahidol University