Fibroblast growth factor-23 abolishes 1,25-dihydroxyvitamin D<inf>3</inf>-enhanced duodenal calcium transport in male mice

• Main Authors: Pissared Khuituan, Jarinthorn Teerapornpuntakit, Kannikar Wongdee, Panan Suntornsaratoon, Nipaporn Konthapakdee, Jintana Sangsaksri, Chanakarn Sripong, Nateetip Krishnamra, Narattaphol Charoenphandhu
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13757

Despite being widely recognized as the important bone-derived phosphaturic hormone, whether fibroblast growth factor (FGF)-23 modulated intestinal calcium absorption remained elusive. Since FGF-23 could reduce the circulating level of 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D3], FGF-23 probably compro...