Meta-analysis of the plasminogen activator inhibitor-1 (PAI-1) gene with insertion/deletion 4G/5G polymorphism and its susceptibility to ischemic stroke in Thai population

• Main Authors: Anunchai Assawamakin, Narin Sriratanaviriyakul, Yupaporn Lalerd, Wanna Thongnoppakhun, Oranud Praditsap, Sissades Tongsima, Manop Pithukpakorn
• Other Authors: Thailand National Center for Genetic Engineering and Biotechnology
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13767
• Institution: Mahidol University

Backgrounds: Plasminogen activator inhibitor-1 (PAI-1) gene was reported to associate with ischemic stroke, particularly the insertion/deletion 4G/5G promoter polymorphism. However, because of the complexity and multifactorial nature of stroke, many previous studies showed inconsistent results. Obje...