UVA-induced melanogenesis and modulation of glutathione redox system in different melanoma cell lines: The protective effect of gallic acid

• Main Authors: Uraiwan Panich, Tasanee Onkoksoong, Saowalak Limsaengurai, Pravit Akarasereenont, Adisak Wongkajornsilp
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine; Physics and Astronomy
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13784

Oxidative stress has been suggested to play a role in ultraviolet A (UVA)-mediated melanogenesis. Glutathione (GSH) and GSH-related enzymes including γ-glutamate cysteine ligase (γ-GCL) and glutathione S-transferase (GST) are important antioxidant defenses responsible for maintaining cellular redox...